Territory of reserve situated in the mountains at the altitude 1000-2000 m, on the slopes of Hazratishoh mountain ridge. The extension of the reserve from north to south is 18 km; from west to east – 25 km. Its territory is unified lot located to the undercurrent of Pyandj River and found on its left bank.
According to the geological division into districts the territory of the reserve located near to the border of Tajik dejection and the Pamirs (including the Darvaz). The relief is indented by deep gorges and streaming down to south west rivers with steep precipitous slopes. Pyandj and Obihingou Rivers are the main water streams on the territory of the reserve.
This climatic belt characterized by less cloudy, dry and hot weather in the summer time and rainy and cool weather conditions in the winter time. The average annual temperature varies within 13-14 degrees. The coldest month is January and the minimal temperature in this month is 22 degrees. The hottest months are June and August with maximal temperature of 40 degrees. The average annual amount of precipitations makes 543 mm and their main amount falls in winter and spring months (December-May).
The main types of bush and forest vegetation in the reserve are: 1. Deciduous mesophilic forests; 2. Small-leaved microterm forests; 3. Tugai forests; 4. Xerophyte hard leaved low forests; 5. Junipers; 6. Summerland bushes; 7. Ephedrs.
Fauna of the reserve represented by 213 species of vertebrates animals including: 1. Mammals - 52 species; 2. Birds - 139 species; 3. Reptiles - 14 species; 4. Fishes - 6 species; 5. Amphibias - 2 ???????????. Following species included to the Red Book of the Republic of Tajikistan: Mammals – Tian Shan Brown Bear, Bukhara sheep (Urial) etc; Birds – Snake eagle, Egyptian vulture, paradise flytrap, bush bird, blue bird; Reptiles – Central Asian cobra, Kufi viper. Such species as snow leopard, Turkistan lynx, Central Asian otter, Markhor, golden eagle, Gypaetus barbatus, redheaded peregrine are included to the Red List of IUCN. The following representative of plants are included to the Red Book of Tajikistan: Korolkov’s saffron, Darvaz iris, extraordinary astragalus, Rozenbach onion, lancet .onion, Suvorov onion, Eduard’s hazel, Maximovich tulip, superior tulip, Tubergen tulip, Afghan fig, ordinary fig, Ovchinnikov’s Highlander, Bukhara empty-headed plant, Vavilov’s almond, Darvaz hawthorn, Darvaz plump and others.